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Open Access Thesis

Keywords

Atherosclerosis; Peripheral vascular diseases;

Abstract

Peripheral arterial disease (PAD) of the lower extremities results from an atherosclerotic process in which the arteries of the lower extremities become narrowed or blocked. The purpose of this study was to identify the prevalence of atherogenic risk factors in patients who have diagnosed PAD of the lower extremities. Specifically, the incidence of the following atherogenic risk factors was examined: parental history of cardiovascular disease, male sex, aging, cigarette smoking, hypertension, diabetes mellitus, and physical inactivity. Each patient was interviewed with a modified Harvard Alumni atherogenic risk factor questionnaire to identify the prevalence of the above mentioned atherogenic risk factors. A noninvasive Doppler Flo-Lab arterial blood flow examination was performed on each patient to determine if they had PAD of the lower extremities, and if so, how severe the disease was. Patients were classified as subjects if the examination revealed PAD of the lower extremities, or if they had undergone previous lower extremity arterial surgery. Data were obtained for 36 subjects. Moderately strong parental history of cardiovascular disease (66.6%females, 77.7% males), cigarette smoking (55.6% females, 88.9% males), hypertension (88.3% females, 44.4% males) especially in females, and sedentary or low physical activity levels (66.6% females, 83.4% males), during the previous 10-30 years was most prevalent in the subjects. Smoking, was also found in males, to show a strong association with severity of PAD of the lower extremities. This was reflected in males by the fact that the number of packs years smoked increased as the severity of the disease increased. In these results were similar to those reported by other researchers, with the exception of diabetes mellitus, which was found in other studies to be a very prevalent atherogenic risk in patients with PAD of the lower extremities. In this study it was prevalent in only 22.2% of females and 5.6% of males. It was concluded that parental history of cardiovascular disease, smoking, hypertension, and physical inactivity over a long period of time have a positive association with PAD of the lower extremities.

Year of Submission

1990

Degree Name

Master of Arts

Department

School of Health, Physical Education, and Leisure Services

First Advisor

William Ryan

Second Advisor

Forrest Dolgener

Third Advisor

David Whitsett

Comments

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Date Original

1990

Object Description

1 PDF file (77 leaves)

Language

en

File Format

application/pdf

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