2024 Summer Undergraduate Research Program (SURP) Symposium
Location
John Deere Auditorium, Curris Business Building, University of Nothern Iowa
Presentation Type
Poster Presentation (UNI Access Only)
Document Type
poster
Abstract
DNA looping within the chromatin structure of Saccharomyces cerevisiae, also known as brewer’s yeast, can be studied using the 3C or “chromosome conformation capture” methodology. Minimal research has been conducted utilizing digital PCR to assess such structures. An analysis of the length-dependence of gene loops, one specific type of DNA looping with physical interactions between promoter and terminator regions of a gene (Figure 1), will provide insights into the mechanical properties of the underlying DNA.
Start Date
26-7-2024 11:00 AM
End Date
26-7-2024 1:30 PM
Event Host
Summer Undergraduate Research Program, University of Northern Iowa
Faculty Advisor
Justin Peters
Department
Department of Chemistry and Biochemistry
Copyright
©2024 Thalia Torres Guzman, Justin Peters
File Format
application/pdf
Recommended Citation
Torres Guzman, Thalia and Peters, Justin, "Gene Looping in Brewer’s Yeast: Exploring the Role of DNA Mechanics in 3D Genome Structure" (2024). Summer Undergraduate Research Program (SURP) Symposium. 31.
https://scholarworks.uni.edu/surp/2024/all/31
Gene Looping in Brewer’s Yeast: Exploring the Role of DNA Mechanics in 3D Genome Structure
John Deere Auditorium, Curris Business Building, University of Nothern Iowa
DNA looping within the chromatin structure of Saccharomyces cerevisiae, also known as brewer’s yeast, can be studied using the 3C or “chromosome conformation capture” methodology. Minimal research has been conducted utilizing digital PCR to assess such structures. An analysis of the length-dependence of gene loops, one specific type of DNA looping with physical interactions between promoter and terminator regions of a gene (Figure 1), will provide insights into the mechanical properties of the underlying DNA.
