Honors Program Theses

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Open Access Honors Program Thesis

First Advisor

Peter Berendzen, Honors Thesis Advisor

Keywords

Catostomidae--Genetics; Catostomidae--Genome mapping; Catostomidae--Evolution;

Abstract

Whole genome duplication (WGD) is a process in which the entire genome of an organism is duplicated, making redundant genes which are subject to unique evolutionary forces. Various modes of selection create different genetic fates such as retention of ancestral function, development of new function, or loss of function. Because of these differing fates, WGD is hypothesized to be a major driving force behind diversification. In this project, DNA sequences from fish species in the family Catostomidae were examined to observe patterns of evolution following a known WGD. Gene trees were generated for 179 loci to determine the amount of divergence among duplicates, revealing divergence to be more common than conservation. Time calibrated phylogenies were generated revealing the date of initial duplicate divergence within the subfamily Ictiobinae to be approximately 63 million years ago. Further analysis could reveal the evolutionary fate of each loci, providing insight into the ways WGD affects diversification.

Year of Submission

2018

Department

Department of Chemistry and Biochemistry

University Honors Designation

A thesis submitted in partial fulfillment of the requirements for the designation University Honors

Date Original

2018

Object Description

1 PDF file (22 pages)

Language

en

File Format

application/pdf

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