Open Access Graduate Research Paper
The efficacy and side effects of olanzapine (an atypical antipsychotic) for the treatment of Schizophrenia were compared over ten different studies. The methods, findings, and limitations of olanzapine treatment when compared to conventional antipsychotics, monotherapy atypical antipsychotics, and combination atypical antipsychotics were addressed. These studies looked at populations of people with first-episode Schizophrenia, chronic cases, and resistant positive and negative symptoms. Olanzapine showed to have an equal to or greater decrease in negative symptoms and also an equal to or greater reduction in positive symptoms. Olanzapine also showed to have a reduction in extrapyramidal symptoms and an increase in neurocognitive functioning, response rates, compliance, and quality oflife. However, olanzapine did have negative side effects such as: significant weight gain, increase in blood pressure and cholesterol, and a decrease in liver function.
Year of Submission
Master of Arts
Educational Leadership, Counseling, and Postsecondary Education
Jan R. Bartlett
1 PDF file (13 pages)
©2009 Jade A. Knutson
Knutson, Jade A., "Olanzapine vs. conventional and other atypical antipsychotics in response and side effects for the treatment of schizophrenia" (2009). Graduate Research Papers. 1012.