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Open Access Graduate Research Paper

Keywords

Olanzapine; Schizophrenia--Treatment;

Abstract

The efficacy and side effects of olanzapine (an atypical antipsychotic) for the treatment of Schizophrenia were compared over ten different studies. The methods, findings, and limitations of olanzapine treatment when compared to conventional antipsychotics, monotherapy atypical antipsychotics, and combination atypical antipsychotics were addressed. These studies looked at populations of people with first-episode Schizophrenia, chronic cases, and resistant positive and negative symptoms. Olanzapine showed to have an equal to or greater decrease in negative symptoms and also an equal to or greater reduction in positive symptoms. Olanzapine also showed to have a reduction in extrapyramidal symptoms and an increase in neurocognitive functioning, response rates, compliance, and quality oflife. However, olanzapine did have negative side effects such as: significant weight gain, increase in blood pressure and cholesterol, and a decrease in liver function.

Year of Submission

2009

Degree Name

Master of Arts

Department

Educational Leadership, Counseling, and Postsecondary Education

First Advisor

Jan R. Bartlett

Comments

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Date Original

2009

Object Description

1 PDF file (13 pages)

Language

EN

File Format

application/pdf

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