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Open Access Thesis

Keywords

Azo dyes--Toxicology; Photocatalysis; Titanium dioxide;

Abstract

C.I. Acid Orange 7 (15510) is the sodium salt of p-[(2-hydroxy-1-naphtalenyl)azo] benzenesulfonic acid. This azo dye is commonly known as Orange II and has been used to dye soaps, shoes, wood and paper (Ramchandani et al., 1994). In the United States and Europe, this dye is not allowed in foodstuffs. The purpose of this study is to investigate the efficiency of a TiO2-mediated photocatalytic oxidation process to degrade Orange II and to determine if Orange II is cytotoxic to certain types of cells. The role of UV radiation and TiO2 particles were examined, as well as the importance of oxygen in the degradation process. The effect of pH was also studied. Human fibroblasts, peripheral blood mononuclear cells (PBMCs) and Jurkat cells (lymphocyte cell line) were used to study Orange II toxicity. Saturation density and MTT (3-( 4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide dye) analysis were used to measure cell growth in the presence of increasing concentrations of Orange IL Orange II concentrations ranged from 2.5 ppm (parts per million) to 200 ppm. Similar analyses were performed on Orange II solutions before and after TiO2-mediated photocatalytic remediation. This was done to determine the efficiency of detoxification. Toxicity was also studied by using Daphnia magna.

Year of Submission

2002

Degree Name

Master of Science

Department

Department of Chemistry

First Advisor

John Bumpus

Second Advisor

Lisa Beltz

Third Advisor

Kavita Dhanwada

Comments

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Date Original

2002

Object Description

1 PDF file (67 leaves)

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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