Dissertations and Theses @ UNI

Availability

Open Access Thesis

Keywords

Biosynthesis; Lichens;

Abstract

The compound 6-bromo-7-hydroxy-2,2,5-trimethylchroman-4-one (1) was desired for use in a project directed toward the synthesis of two novel depsidones. Since 7-hydroxy-2,2,5-trimethylchroman-4-one (2) was readily available, a number of bromination conditions were investigated in an attempt to find a regiospecific synthesis of 1. However, mixtures of varying composition of 1, 2, 3 and 4 were obtained under all the conditions tried. Final separation of 1 and its isomer 3 was accomplished by a mixture of chromatographic techniques. Structural assignment of the two brominated products 1 and 3 was made by a combination of carbon and proton NMR.

Year of Submission

1978

Degree Name

Master of Arts

Department

Department of Chemistry

First Advisor

James MacMillan

Second Advisor

James Chang

Third Advisor

Clifford G. McCollum

Comments

If you are the rightful copyright holder of this thesis and wish to have it removed from the Open Access Collection, please submit a request to scholarworks@uni.edu and include clear identification of the work, preferably with URL.

Date Original

1978

Object Description

1 PDF file (69 leaves)

Language

en

File Format

application/pdf

Included in

Chemistry Commons

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