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Open Access Thesis

Keywords

Ionization; Time-of-flight mass spectrometry; Academic theses;

Abstract

Laser desorption has been an important tool in mass spectrometry. It has been known that an order of magnitude more neutrals than ions are produced during laser desorption. A Time-Of-Flight Mass Spectrometer with an infinitely adjustable acceleration region was constructed to map the population distribution of neutral ion precursors and metastable ions in the flight tube. Desorption was performed by using a nitrogen UV laser at 337 nm. Experiments conclude that the majority of post-source ionization of neutrals occurs approximately 2.5 cm from the sample-laser interface. The intensity of ions tapers rapidly out to 6.0 cm, however ions were detected as far as 17.0 cm from the sample interface. The calculated field free drift rate of sodium and cesium neutral precursors is consistent with prior research, and kinetic energy screening of the ions show that cesium ions have a lower kinetic energy than cesium iodide clusters. This gives evidence to the meta-stable decay of cesium iodide neutral precursors after ionization. These studies provide additional insight into the kinetics of ion formation and fragmentation during laser desorption. Additional research could yield evidence of the rate of formation of ions from neutral precursors.

Year of Submission

2012

Degree Name

Master of Science

Department

Department of Chemistry and Biochemistry

First Advisor

Curtiss D. Hanson

Second Advisor

R. Martin Chin

Third Advisor

Jeffrey Elbert

Comments

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Date Original

2012

Object Description

1 PDF file (108 leaves)

Language

en

File Format

application/pdf

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