Dissertations and Theses @ UNI
Availability
Open Access Thesis
Keywords
Athletes--Drug use; Ephedrine--Physiological effect;
Abstract
To determine the effect of a greater than therapeutic dose of ephedrine HCl on short term high-intensity running, 10 University Division I male track athletes (mean age 22.9 ± 1.8 years) were tested on two occasions. The study was double-blind and placebo controlled. Subjects ingested a capsule containing ephedrine HCl (75 mg/70 kg body weight) on one test date and alternately ingested a placebo capsule on the opposite test date. Subjects then sat quietly for 60 min while measurements of heart rate, blood pressure and electrocardiographic response were taken at 20 min intervals. A sample of blood was taken from the fingertip at 60-min post-ingestion and analyzed for blood lactate concentration. At 70-min post-ingestion, subjects performed a maximal treadmill test to determine maximal oxygen consumption (VO2max), respiratory exchange ratio (RER), and time to exhaustion. Treadmill testing consisted of an initial velocity of 6.0 mph (2.68 m/s) and grade of 0% followed by a 1.0 mph (0.45 m/s) increase in velocity and 2% increase in grade every 2 min. At 5 min post-exercise, blood lactate measurement was taken. A repeated measures ANOVA was used to compare placebo and treatment data. There were no significant differences found between treatment and control trials (p>.05 for all variables tested). Time to exhaustion in the treatment trial was 3.12 ± 0.13 min and 3.05 + 0.20 min in the placebo trial. These results indicate that ephedrine HCl dosed at 75 mg/70 kg has no significant effect on time to exhaustion· during high intensity running. Furthermore, the results suggest ephedrine HCl, at the given dose, has no significant effect on the physiological parameters tested.
Year of Submission
1995
Degree Name
Master of Arts
Department
School of Health, Physical Education, and Leisure Services
First Advisor
Forrest Dolgener
Second Advisor
Fred Kolkhorst
Third Advisor
Sue Joslyn
Date Original
1995
Object Description
1 PDF file (74 leaves)
Copyright
©1995 John T. Voelz
Language
en
File Format
application/pdf
Recommended Citation
Voelz, John T., "The Effect of High-Dose Ephedrine Hydrochloride on High-Intensity Treadmill Performance" (1995). Dissertations and Theses @ UNI. 1895.
https://scholarworks.uni.edu/etd/1895
Comments
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