Synthesis and Antibacterial Studies of Some 2-Furanthiocarboxyhydrazones

Authors

Xiaorong Li, Shaanxi Teachers UniversityFollow
Zoumin Sun, Shaanxi Teachers UniversityFollow
James C. Chang, University of Northern IowaFollow

Document Type

Research

Keywords

2-Furanthiocarboxyhydrazones, antibacterial studies

Abstract

Seven 2-furanthiocarboxyhydrazones were prepared, 5-nitro-furaldehyde-2-furanthiocarboxyhydrazone from the reaction of 2-furanthiocarboxyhydrazide with 5-nitro-2-furaldiacetate and the others from the condensation of 2-furanthiocarboxyhydrazide with aldehydes: 2- furaldehyde, benzaldehyde, p-hydroxybenzaldehyde, o-methoxybenzaldehyde, o-vanillin, and salicylaldehyde. The seven 2-furanthiocarboxyhydrazones were tested for their antibacterial activities against Staphyloccocus aureus and Bacillus subtilis. 5-Nitro-2-furaldehyde-2- furanthiocarboxyhydrazone was found to display the strongest bacterotoxicity.

Publication Date

June 1989

Journal Title

Journal of the Iowa Academy of Science

Volume

96

Issue

2

First Page

65

Last Page

66

Copyright

© Copyright 1989 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

Recommended Citation

Li, Xiaorong; Sun, Zoumin; and Chang, James C. (1989) "Synthesis and Antibacterial Studies of Some 2-Furanthiocarboxyhydrazones," Journal of the Iowa Academy of Science: JIAS, 96(2), 65-66.
Available at: https://scholarworks.uni.edu/jias/vol96/iss2/9