Home > Iowa Academy of Science > Journals & Newsletters > Proceedings of the Iowa Academy of Science > Volume 80 (1973) > Number 3
Document Type
Research
Keywords
Thyroxine, chick limb bud, ectoderm-meso-derm interaction, RNA, acid phosphatase
Abstract
Transplanted hind limb buds of chick embryos at stage18 were treated with thyroxine, which caused complete growth inhibition at concentrations of 200, 150, and 100 μg/ml. Lower concentrations caused reduction in length and weight as well as decreased number of feather germs. An increase in the enzyme acid phosphatase and number of lysosomes, in the cells of limb buds, were also observed. Increased acid phosphatase reaction was accompanied by decreased amounts of RNA (in treatment with 50 and 70 μg/ml. concentrations), suggesting a correlation between the two thus showing a thyroxine effect on lysosome activity.
Publication Date
September 1973
Journal Title
Proceedings of the Iowa Academy of Science
Volume
80
Issue
3
First Page
140
Last Page
144
Copyright
©1973 Iowa Academy of Science, Inc.
Language
en
File Format
application/pdf
Recommended Citation
Suleiman, Suleiman A.
(1973)
"Effect of Thyroxine on Early Development of Chick Limb Buds,"
Proceedings of the Iowa Academy of Science, 80(3), 140-144.
Available at:
https://scholarworks.uni.edu/pias/vol80/iss3/8