The Effects of 2-Deoxyglucose on the ATP Consumption in Cell Cultures

Authors

Darrell D. Young, New York State UniversityFollow

Document Type

Research

Keywords

2-Deoxyglucose, mitotic index, adenosine triphosphate, cell cultures, Swann's "energy reservoir" hypothesis

Abstract

Cultures of Chinese Hamster Cells (CCL 16, Don Strain) were treated with 2-Deoxyglucose over varying lengths of time in order to compare the mitotic index with the rate of adenosine triphosphate synthesis. Treatment with the glucose analog reduces both the mitotic index and the ATP level by nearly 50 percent. The relationship to the Swann "energy reservoir" hypothesis is also discussed.

Publication Date

April 1972

Journal Title

Proceedings of the Iowa Academy of Science

Volume

79

Issue

1

First Page

41

Last Page

43

Copyright

©1972 Iowa Academy of Science, Inc.

Language

en

File Format

application/pdf

Recommended Citation

Young, Darrell D. (1972) "The Effects of 2-Deoxyglucose on the ATP Consumption in Cell Cultures," Proceedings of the Iowa Academy of Science, 79(1), 41-43.
Available at: https://scholarworks.uni.edu/pias/vol79/iss1/13