Salicyclic acid, chick limb bud, ectodermmesodern interaction, limb bud growth
Transplanted hind limb-buds of chick embryos were treated with salicylic acid. Treatment with this chemical caused reduction in length, weight and volume of the developing limb-buds. A side effect observed was an apparent loosening of the basal membrane and examined with regard to length, weight, and volume. The above observations are discussed in relation to the different hypotheses of the ectoderm-mesoderm interaction. The physiological role of the basal membrane, as well as the possible implications of the basal findings to the question of limb development and morphogenesis, are also discussed.
Proceedings of the Iowa Academy of Science
©1971 Iowa Academy of Science, Inc.
Suleiman, Suleiman A. and Baker, John R.
"Effect of Salicylic Acid on the Early Development of the Chick Limb-Bud,"
Proceedings of the Iowa Academy of Science, 78(1-2), 20-23.
Available at: https://scholarworks.uni.edu/pias/vol78/iss1/9