Isolated stomachs from mammals showed substantial active absorption of sodium (Am.J. Dig. Dis. 14:221-238, 1969) in contrast to isolated frog gastric mucosa. Could the difference have been due to a "micro-environment" in the latter preparation based on fine structure features that maintained high H-ion concentration at the site of active transport? To answer this, H-ion secretion was inhibited in frog gastric mucosa with 15 mM thiocyanate. Unidirectional fluxes of sodium were not materially affected. These results cast doubt on a possible depression of active sodium absorption by a high H-ion concentration in the "microenvironment" of the isolated amphibian mucosa.
Proceedings of the Iowa Academy of Science
© Copyright 1970 by the Iowa Academy of Science, Inc.
Hogben, C. Adrian M.
"Failure of Thiocyanate to Influence The Flux of Sodium Through The Isolated Frog Gastric Mucosa,"
Proceedings of the Iowa Academy of Science, 77(1), 137-140.
Available at: https://scholarworks.uni.edu/pias/vol77/iss1/20