Exposure of white mice (Swiss Webster, female; NLW, male and female) to 1.5 to 7.0 G's of chronic centrifugation from the age of 5 weeks for durations of 1 to 8 weeks is known to cause some reduction in body growth. However, the retardation of muscular development was not as drastic. When corrections were made for differences between experimental and control body mass by means of Huxley's Equation for Heterauxic Growth, the muscles of experimental mice were seen to be larger than those of control animals of the same size. The measurements of muscle size, in order of increasing high-G response were: wet mass, dry mass, and noncollagen nitrogen (NCN) content. These data were examined in terms of the Huxley Heterauxic Equation, as modified from a consideration of Galileo's Principle of Similitude:
muscle size ∝(inertial field) (body mass)4/3.
Although all experimental muscle measurements (relative to constant body size) increased with centrifugation, any single detected compensation was much less than the total compensation predicted by this equation. The best empirical relationship found for high-G data was a linear one between the logarithm of effect upon muscles size and logarithm of effect upon body size.
Proceedings of the Iowa Academy of Science
© Copyright 1969 by the Iowa Academy of Science, Inc.
Wunder, Charles C. and Bird, John W. C.
"Growth of the White-Mouse Gastrocnemius Muscle II. In Non-Terrestrial Gravity,"
Proceedings of the Iowa Academy of Science: Vol. 76:
, Article 49.
Available at: https://scholarworks.uni.edu/pias/vol76/iss1/49