Document Type

Research

Abstract

Extensive investigations were conducted on the development of a microbiological assay of a vitamin B₆ antagonist found in flaxseed. It is the only known naturally occurring inhibitor of vitamin B₆. By means of a screening procedure, ten microorganisms were found to be inhibited by preparations of the B₆ antagonist. One of these, Bacillus polymyxa, was investigated more fully. Correlations of the B. polymyxa and live chick assays were excellent. All column chromatographic fractions of inhibitor which reduced Tollen's reagent inhibited B. polymyxa. Vitamin B₆ does not competitively reverse the bacterial inhibition. Inhibition of B. polymyxa by high levels of Vitamin B₆ and the B₆ antagonist may suggest that the antagonist is an analogue of the vitamin.

Publication Date

1965

Journal Title

Proceedings of the Iowa Academy of Science

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application/pdf

Recommended Citation

Tjostem, John L. (1965) "Microbiological Studies on the Vitamin B6 Antagonist Found in Flaxseed," Proceedings of the Iowa Academy of Science, 72(1), 51-62.
Available at: https://scholarworks.uni.edu/pias/vol72/iss1/12

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Microbiological Studies on the Vitamin B6 Antagonist Found in Flaxseed

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