The Effects of Phlorizin, 2,4-dinitrophenol, and Oxygen Deprivation on the Intestinal Transport of D-glucose

Authors

Alice Marie Fox, Clarke CollegeFollow

Document Type

Research

Abstract

The effect of various concentrations of phlorizin and 2,4-dinitrophenol, plus the effect of oxygen deprivation on intestinal absorption of D-glucose was investigated. Paired segments of turtle (Chrysemys picta) small intestine in vitro were used. Preparations were incubated for one hour in a shaking water bath at 30°C in Krebs-Ringer-bicarbonate, with or without inhibitor. Phlorizin, in all concentrations used, was found to prevent uptake of glucose by the mucosal epithelium. Inhibition also occurred, in a lesser degree, with 2,4-dinitrophenol, and when the system was flushed with nitrogen instead of air.

Publication Date

1963

Journal Title

Proceedings of the Iowa Academy of Science

Volume

70

Issue

1

First Page

423

Last Page

427

Copyright

©1963 Iowa Academy of Science, Inc.

Language

en

File Format

application/pdf

Recommended Citation

Fox, Alice Marie (1963) "The Effects of Phlorizin, 2,4-dinitrophenol, and Oxygen Deprivation on the Intestinal Transport of D-glucose," Proceedings of the Iowa Academy of Science, 70(1), 423-427.
Available at: https://scholarworks.uni.edu/pias/vol70/iss1/69