Aqueous solutions of the potassium salts of diethyl thiophosphate and diethyl dithiophosphate were applied to intact leaves of the following 10 plant species: alfalfa (Medicago saliva L.), carrot (Daucus carota L.), strawberry (Fragaria chiloensis, Duchesne), American elderberry (Sambucus canadensis L.), velvetleaf (Abutilon theophrasti Medic.), dandelion (Taraxacum officinale Weber), soybean (Glycine max, Merr.), lima bean (Phaseolus limensis Macf.), catnip (Nepeta cataria L.), and Virginia creeper (Hedera quinquefolia L.). After 24 to 72 hours, aqueous homogenates of all species, excepting carrot, inhibited the action of human plasma cholinesterase in vitro. Neither the plant homogenates nor the thiophosphate salts either separately or mixed brought about inhibition. It is postulated that dialkyl thio- or dithiophosphates are incorporated by intact living plant tissue into cholinesterase-inhibitory esters.
Proceedings of the Iowa Academy of Science
© Copyright 1959 by the Iowa Academy of Science, Inc.
Orgell, Wallace H.; Vaidya, Kunda A.; and Hamilton, Eugene W.
"Biosynthesis of Cholinesterase-inhibitory Substances from Non-inhibitory Dialkyl Thiophosphates by Plant Tissues,"
Proceedings of the Iowa Academy of Science, 66(1), 145-148.
Available at: https://scholarworks.uni.edu/pias/vol66/iss1/19