In recent years the use of morpholine and sulfur in the Willgerodt reaction has received considerable attention. There have been several mechanisms proposed for the Willgerodt reaction, but the most generally accepted mechanism today is that outlined by King and McMillan1. These authors have attempted to show that an independent reaction between sulfur and the amine is essential to this reaction. They have postulated an amine sulfide intermediate similar to the already known amine oxides. These sulfides have not been isolated as by-products of the reaction nor have they been prepared in any other way. The only previous evidence of a reaction between sulfur and morpholine is the formation of dithiooxalodi-morpholide reported by Horton and Van den Berghe2.
Proceedings of the Iowa Academy of Science
©1950 Iowa Academy of Science, Inc.
Peters, Edward M. and Smith, Watler T. Jr.
"The Formation of Morpholine Thiosulfate From Morpholine and Sulfur,"
Proceedings of the Iowa Academy of Science, 57(1), 211-213.
Available at: https://scholarworks.uni.edu/pias/vol57/iss1/23