The Production of Kynurenic Acid from Tryptophane and Indole Derivatives

Authors

Lyle C. Bauguess, State University of IowaFollow
Clarence P. Berg, State University of IowaFollow

Document Type

Research

Abstract

The production of kynurenic acid from derivatives closely related to tryptophane serves as a means of indicating whether the animal organism is able to accomplish the changes necessary to convert such derivatives into tryptophane itself, or into some product intermediate in the transformation of tryptophane to kynurertic acid. With this in mind, a number of l-tryptophane and indole derivatives were prepared and administered to rabbits, both per os and subcutaneously, in amounts molecularly equivalent to 1 gm. of tryptophane and the kynurenic acid produced was estimated.

Publication Date

1934

Journal Title

Proceedings of the Iowa Academy of Science

Volume

41

Issue

1

First Page

174

Last Page

175

Copyright

©1934 Iowa Academy of Science, Inc.

Language

en

File Format

application/pdf

Recommended Citation

Bauguess, Lyle C. and Berg, Clarence P. (1934) "The Production of Kynurenic Acid from Tryptophane and Indole Derivatives," Proceedings of the Iowa Academy of Science, 41(1), 174-175.
Available at: https://scholarworks.uni.edu/pias/vol41/iss1/60