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Document Type

Research

Abstract

A comparison of the velocities of hydrolysis of the 2-, the 3- and the 4-methyl diphenyl ketimine hydrochlorides, in which the velocity of the first is very much slower than either of the other two, suggests steric hindrance. The very slow rate of hydrolysis of 2, 4, 6-trihydroxy diphenyl ketimine hydrochloride has been reported by one of us. This slow rate may be accounted for on the basis of the multiple opportunities for tautomerism involving the very stable enamine forms. We have recently found 2-methyl, 4, 6-dihydroxy di phenyl (orcinyl phenyl) ketimine hydrochloride to be even more slowly hydrolyzed. It would appear here that the steric hindrance effect outweighs the possible enamine tautomerism.

Publication Date

1933

Journal Title

Proceedings of the Iowa Academy of Science

Volume

40

Issue

1

First Page

113

Last Page

113

Copyright

© Copyright 1933 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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