Tetra-ethyl furantetracarboxylate is readily prepared by the condensation of oxalacetic ester. The corresponding furantetracarboxylic acid can be progressively decarboxylated. Two of the interesting products of decarboxylation are 3, 4-furandicarboxylic acid and 3-furoic acid. The 3, 4-furandicarboxylic acid is interesting not only for purposes of absolute orientation (it completes the series of furandicarboxylic acids) but also because it gives unequivocal evidence for the constitution of a series of 2-nitrofurans. It now appears that this method of stripping carboxyl groups is the best now available for the synthesis of 3-furoic acid, which otherwise is prepared with considerable difficulty.
Proceedings of the Iowa Academy of Science
© Copyright 1933 by the Iowa Academy of Science, Inc.
Gilman, Henry; Oatfield, Harold; and Kirkpatrick, Willard H.
"The Progessive and Step-Wise Decarboxylation of Furan-Tetracarboxlic Acid,"
Proceedings of the Iowa Academy of Science, 40(1), 112-112.
Available at: https://scholarworks.uni.edu/pias/vol40/iss1/52