Interest in the possibility of replacing essential amino acids in the diet with synthetic products more or less closely related in chemical structure has led us to synthesize β -3-indoleacrylic acid and α-oximino-β-3-indolepropionic acid and feed them to rats in conjunction with a diet deficient in tryptophane. Reports in the literature on the availability of β-4-imidazoleacrylic acid in supplementing diets deficient in histidine are conflicting. No α-oximino acid has been studied in this connection. The oxime of pyruvic acid, however, has been shown to undergo reduction, in the presence of vigorously fermenting yeast, to alanine.
Proceedings of the Iowa Academy of Science
©1933 Iowa Academy of Science, Inc.
Bauguess, Lyle C. and Berg, Clarence P.
"The Availabilty of Indole Derivatives for Supplementing Diets Derivatives in Tryptophane,"
Proceedings of the Iowa Academy of Science, 40(1), 110-111.
Available at: https://scholarworks.uni.edu/pias/vol40/iss1/50