The ovaries of Rana clamitans larvae show marked degenerative changes after x-ray treatment with lethal doses. These animals live from three to four weeks after exposure and death is usually accompanied by characteristic pathological changes in the epidermis and viscera. The ovary becomes smaller and in young animals its further development is arrested. The oogonia are most resistant to x-rays and exhibit very little change but the growing young eggs are completely disintegrated probably by changes in their chemical composition. The larger auxocytes also degenerate by a process of vacuolization and finally appear as cells of a fibrous skeletal structure. The nucleus and yolk body are abnormal. These changes are followed by an increase in the interstitial and rete tissues which tend to obliterate the ovarial cavity. Several cases have been observed, where there is a tendency toward the formation of a testis-like structure. The effects of less than lethal doses will shed more light on this phenomenon.
Proceedings of the Iowa Academy of Science
©1931 Iowa Academy of Science, Inc.
Levine, William T.
"Retrogressive Changes in the Ovaries of Rana clamitans Tadpoles following X-Ray Treatment,"
Proceedings of the Iowa Academy of Science, 38(1), 287-288.
Available at: https://scholarworks.uni.edu/pias/vol38/iss1/104