•  
  •  
 

Document Type

Research

Abstract

These syntheses were carried out through the action of the corresponding hydroxy-nitrile upon magnesium phenyl bromide in an anhydrous ether medium. Over two equivalents of the Grignard reagent were employed, one to react with the phenol group and the other with the nitrile. The addition compound was decomposed with water and ammonium chloride at about -15 degrees C. The ketimine extracted with ether was precipitated as the hydrochloride by the addition of dry hydrogen chloride. The hydroxynitriles were prepared from the corresponding hydroxy-aldehydes by the action of acetic anhydride on their oximes. Some modifications were worked out in the preparation of the oximes and the nitriles.

Publication Date

1929

Journal Title

Proceedings of the Iowa Academy of Science

Volume

36

Issue

1

First Page

266

Last Page

267

Copyright

©1929 Iowa Academy of Science, Inc.

Language

en

File Format

application/pdf

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.