Monobromovanillin was prepared by Carles (Bull. Soc. Chim., 17, 12 (1872) and further investigated by Tiemann and Haarman (Ber., 7, 615 (1874). More recently, Brady and Dunn CJ. Chem. Soc., 107, 1859 (1915) studied the corresponding oxime, which was found to exist in but one of the stereoisomeric forms required by the theory. In the present work a dibromo derivative of vanillin, which has not hitherto been reported, has been prepared by a method that gives a high yield. Among its derivatives it has been found that the oxime exists in but one form, and that the nitril obtained from it resists hydrolysis to an extraordinary degree. The determination of the structure of the dibromo compound is in progress.
Proceedings of the Iowa Academy of Science
©1926 Iowa Academy of Science, Inc.
Hilman, G. Carroll and Alderks, O. H.
"New Derivatives of Vanillin,"
Proceedings of the Iowa Academy of Science, 33(1), 175-175.
Available at: https://scholarworks.uni.edu/pias/vol33/iss1/32