Analog Parallel Processing of Molecular Sensory Information

Authors

Nalin C.W. Goonesekere, University of ColomboFollow
A. Prasanna de Silva, Queen's University
S. Sisira K. de Silva, University of Colombo
H. Q. Nimal Gunaratne, Queen's University
P. L. Mark Lynch, Queen's University
Kemuel R. Nesbitt, Queen's University
Suram T. Patuwathavithana, University of Colombo
N. L.D. Sydney Ramyalal, University of Colombo

Document Type

Article

Keywords

Absorption, Fluorescence, Imaging probes, Molecular dynamics, Sensors

Journal/Book/Conference Title

Journal of the American Chemical Society

Volume

129

Issue

11

First Page

3050

Last Page

3051

Abstract

Multiple fluorescent PET (photoinduced electron transfer) sensors of predictively known analyte binding constants are run in parallel to give a large quasilinear dynamic range. The specific case of proton analytes is demonstrated with four near-optimal sensors to produce a range of ca. 9 pH units. Thus, sets of molecular sensors can be persuaded to respond like ion selective electrodes while maintaining the advantages of nanosize and imaging ability.

Department

Department of Chemistry and Biochemistry

Original Publication Date

2-21-2007

DOI of published version

10.1021/ja0686514

Recommended Citation

Goonesekere, Nalin C.W.; Prasanna de Silva, A.; Sisira K. de Silva, S.; Nimal Gunaratne, H. Q.; Mark Lynch, P. L.; Nesbitt, Kemuel R.; Patuwathavithana, Suram T.; and Sydney Ramyalal, N. L.D., "Analog Parallel Processing of Molecular Sensory Information" (2007). Faculty Publications. 6330.
https://scholarworks.uni.edu/facpub/6330