Leaf Form Diversification In An Ornamental Heirloom Tomato Results From Alterations In Two Different Homeobox Genes

Authors

Hokuto Nakayama, Department of Plant Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Steven D. Rowland, Department of Plant Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Zizhang Cheng, Department of Plant Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Kristina Zumstein, Department of Plant Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA.
Julie Kang, Biology Department, University of Northern Iowa, 144 McCollum Science Hall, Cedar Falls, IA 50614, USA.Follow
Yohei Kondo, Division of Quantitative Biology, Okazaki Institute for Integrative Bioscience, National Institute for Basic Biology, National Institutes of Natural Sciences, Myodaiji, Higashiyama 5-1, Okazaki, Aichi 444-8787, Japan.
Neelima R. Sinha, Department of Plant Biology, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA. Electronic address: nrsinha@ucdavis.edu.Follow

Document Type

Article

Publication Version

Author Accepted Manuscript

Keywords

BEL-LIKE HOMEODOMAIN, HOMEOBOX gene, SOLANIFOLIA, Solanum lycopersicum, WUSCHEL RELATED HOMEOBOX 1, evolution, heirloom tomato, leaf

Journal/Book/Conference Title

Current biology: CB

Abstract

Domesticated plants display diverse phenotypic traits. However, the influence of breeding effort on this phenotypic diversity remains unknown. Here, we demonstrate that a single nucleotide deletion in the homeobox motif of BIPINNATA, a BEL-LIKE HOMEODOMAIN gene, led to a highly complex leaf phenotype in an heirloom tomato (Solanum lycopersicum), Silvery Fir Tree (SiFT), which is used as a landscaping and ornamental plant. A comparative gene network analysis revealed that repression of SOLANIFOLIA, the ortholog of WUSCHEL RELATED HOMEOBOX 1, caused the narrow leaflet phenotype seen in SiFT. Comparative genomics indicated that the bip mutation in SiFT likely arose de novo and is unique to SiFT and not introgressed from other tomato genomes. These results provide new insights into the natural variation in phenotypic traits introduced into crops during improvement processes after domestication and establish homeobox genes as evolutionary hotspots.

Department

Department of Biology

Original Publication Date

9-3-2021

Object Description

1 PDF file

DOI of published version

10.1016/j.cub.2021.08.023

Repository

UNI ScholarWorks, Rod Library, University of Northern Iowa

Date Digital

9-3-2021

Copyright

©2021 Nakayama et al

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

Language

en

File Format

application/pdf

Recommended Citation

Nakayama, Hokuto; Rowland, Steven D.; Cheng, Zizhang; Zumstein, Kristina; Kang, Julie; Kondo, Yohei; and Sinha, Neelima R., "Leaf Form Diversification In An Ornamental Heirloom Tomato Results From Alterations In Two Different Homeobox Genes" (2021). Faculty Publications. 4.
https://scholarworks.uni.edu/facpub/4