Award/Availability

Open Access Honors Program Thesis

First Advisor

Melisa M. Cherney

Keywords

Cytochrome C; Ligand binding (Biochemistry); Protein binding;

Abstract

The purpose of this research was to create a simpler model of Type II proteins in order to study the ligand switch using cytochrome c (Figure 3). Cytochrome c was chosen because it is small, easy to work with, and relatively easy to mutate. It also already has a built-­­in mechanism for a ligand switch, making it the ideal candidate for this protein model. Mutating cytochrome c into a model Type II protein and learning more about how the ligand switch controls function may generate new insight into how the corresponding ligand switch works in more complex proteins.

Date of Award

2013

Department

Department of Chemistry and Biochemistry

University Honors Designation

A thesis submitted in partial fulfillment of the requirements for the designation University Honors

Date Original

2013

Object Description

1 PDF file (49 pages)

Language

EN

File Format

application/pdf

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