Effects of a Home-Based Intervention on HIV Prevention Health Behaviors in Pregnant/Postpartum Kenyan Women: Estimating Moderating Effects of Depressive Symptoms
Depressive symptoms, HIV, Home-based, Maternal health
AIDS and Behavior
We estimated effects of maternal depressive symptoms, utilizing the Patient Health Questionnaire-8 (PHQ-8), on women’s HIV prevention behaviors in Migori County, Kenya. Pregnant women ≥ 18 years old, with gestational age of < 37 weeks, were randomized into standard care or three home visits (2 during pregnancy, 1 postpartum) promoting couple HIV testing and counseling (CHTC) and HIV prevention. Of 105 female participants, 37 (35.24%) reported depressive symptoms and 50 (47.62%) were HIV-positive. Three Poisson regressions with robust variance (univariable, multivariable, and multivariable with depressive symptoms/study arm interaction) were modeled for three outcomes: CHTC, infant HIV testing, health-seeking postpartum. In multivariable analysis with interaction, a moderating trend for the interaction between depressive symptoms and individual health-seeking was observed (p-value = 0.067). Women scoring ≤ 9 (n = 68) on the PHQ-8 and participating in home visits were 1.76 times more likely to participate in individual health-seeking compared to participants in standard care (ARR 1.76, 95% CI 1.17–2.66).
Center for Social and Behavioral Research
Original Publication Date
DOI of published version
UNI ScholarWorks, Rod Library, University of Northern Iowa
Anderson, Jami L.; Li, Peng; Bukusi, Elizabeth A.; Darbes, Lynae A.; Hatcher, Abigail M.; Helova, Anna; Kwena, Zachary A.; Musoke, Pamela L.; Owino, George; Oyaro, Patrick; Rogers, Anna Joy G.; and Turan, Janet M., "Effects of a Home-Based Intervention on HIV Prevention Health Behaviors in Pregnant/Postpartum Kenyan Women: Estimating Moderating Effects of Depressive Symptoms" (2021). Faculty Publications. 89.