Work leading toward the preparation of this and if possible toward one of its isomers, was commenced with work on phenol. First the phenyl acetate was made as follows: forty-one grams of phenol were taken in a distilling flask, and to this were added gradually, through a reflux condenser (in hood) twenty-eight to thirty grams (excess) of acetyl chloride. The flask was heated in a water-bath until the HC1 ceased to come off. The contents of the flask were then washed with a dilute solution of sodium hydroxide brought into a separating funnel with water, and the oil separated, dried over calcium chloride and distilled. B. p. = 195°. Yield forty grams.
Proceedings of the Iowa Academy of Sciences
©1901 Iowa Academy of Science, Inc.
Goodwin, J. G.
"Paroxymetamethylacetophenone and Some of Its Derivatives,"
Proceedings of the Iowa Academy of Science, 9(1), 113-119.
Available at: https://scholarworks.uni.edu/pias/vol9/iss1/19