2-Deoxyglucose, mitotic index, adenosine triphosphate, cell cultures, Swann's "energy reservoir" hypothesis
Cultures of Chinese Hamster Cells (CCL 16, Don Strain) were treated with 2-Deoxyglucose over varying lengths of time in order to compare the mitotic index with the rate of adenosine triphosphate synthesis. Treatment with the glucose analog reduces both the mitotic index and the ATP level by nearly 50 percent. The relationship to the Swann "energy reservoir" hypothesis is also discussed.
Proceedings of the Iowa Academy of Science
©1972 Iowa Academy of Science, Inc.
Young, Darrell D.
"The Effects of 2-Deoxyglucose on the ATP Consumption in Cell Cultures,"
Proceedings of the Iowa Academy of Science, 79(1), 41-43.
Available at: https://scholarworks.uni.edu/pias/vol79/iss1/13