The experiments indicate that when DMSO-Ringer's solutions are applied to the outside of the frog skin, the electrical potential difference across the skin decreases while the short circuiting current increases slightly. Ringer's solutions containing DMSO applied to the inside of the skin caused both the short circuiting current and the potential difference across the skin to decrease. These observations appear to be directly related to the concentration of DMSO-Ringer's applied. The observed effects are discussed with respect to possible changes in the skin brought about by the DMSO and the relationships of these phenomena to active transport functions of the skin.
Proceedings of the Iowa Academy of Science
© Copyright 1970 by the Iowa Academy of Science, Inc.
Baumann, David M. and Dunham, Jewett
"Transitory Effects of Dimethyl Sulfoxide on the Electrical Properties of Isolated Frog Skin,"
Proceedings of the Iowa Academy of Science, 77(1), 141-148.
Available at: https://scholarworks.uni.edu/pias/vol77/iss1/21