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Document Type

Research

Abstract

Administration of the antithyroid drug, propylthiouracil (PTU), to albino male rats at the dietary level of 0.1 % PTU is accompanied by a decrease in growth rate and a decrease in the oxygen consumption rate. After the initial administration of PTU, prolonged treatment with the drug did not further lower the oxygen consumption rate. The ratios of organ weight to body weight for the testes, stomach, thyroid, eyes, pituitary, and brain were found to be larger in the treated rats than in the untreated controls. The organ weight to body weight ratios of the spleen, liver, kidneys, and heart were smaller in the PTU treated rats than in the untreated controls examined.

Publication Date

1969

Journal Title

Proceedings of the Iowa Academy of Science

Volume

76

Issue

1

First Page

361

Last Page

367

Copyright

© Copyright 1969 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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