Eleven male rats were subjected to jejunectomy under ether anesthesia with end-to-end intestinal anastomosis. After recovery they were allowed to eat ad libitum and growth was little impaired. An in vivo test of absorptive capacity for glucose was applied to the surviving ileum of the jejunectomized animals and to the corresponding segment of ileum in eleven untreated rats. The correlation coefficient for the body weight and the amount of glucose absorbed from a Krebs-Ringer-bicarbonate solution containing 16 to 17 μmol/ml (300 mg. percent) glucose in all animals was 0.45. Accordingly, absorption of glucose and of fluid volume was expressed as amounts absorbed/100 gm. body weight/one hour test. Fluid volume absorbed followed the amount of glucose absorbed; the correlation coefficient between these parameters was 0.94. The ileal absorptive capacity for glucose significantly increased in five rats tested about 74 days post-jejunectomy compared to that in the 11 control animals. Six rats tested about 147 days post-operatively showed significantly less absorptive capacity than the shorter term group, and less, though not significantly, than the control group. Possible factors underlying these results are discussed.
Proceedings of the Iowa Academy of Science
©1968 Iowa Academy of Science, Inc.
Kelly, William M. and Searle, Gordon W.
"IIeal Glucose Absorption After Jejunectomy in the Rat,"
Proceedings of the Iowa Academy of Science, 75(1), 291-295.
Available at: https://scholarworks.uni.edu/pias/vol75/iss1/39