Propylene oxide sterilization of media containing soil bacterial populations occurred after 11 hours exposure in a closed system. Population reaction to the sterilant was characterized by inhibition intervals in the sterilization process. These stages represent minimal survival rates of 70%, 40%, and 7% respectively. A sterilization threshold (less than 1% survivors) occurred between 8-10 hours. Homogenous populations of Bacillus subtilis showed survival values in the first inhibition interval until the 4th hour. Lethality was noted at the 5th hour of exposure and other stages observed in heterogeneous populations did not occur.
Proceedings of the Iowa Academy of Science
©1967 Iowa Academy of Science, Inc.
Naylon, Micheal J. and Goss, Robert C.
"Propylene Oxide Sterilization of Media Containing Bacterial Populations,"
Proceedings of the Iowa Academy of Science, 74(1), 20-25.
Available at: https://scholarworks.uni.edu/pias/vol74/iss1/7