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Document Type

Research

Abstract

The antithyroid drug, Tapazole (methamazole, or imidazole-2-thio, 1-methyl), when fed to female rats at the dietary level of 0.1 % had a slight effect on the average number of young and weight per litter if administered during the preconception period. If given during the gestation period the results were harmful. Tapazole treatment of mothers during lactation resulted in lethargic cretin-like young, although survival rates during lactation and after weaning were good.

Publication Date

1965

Journal Title

Proceedings of the Iowa Academy of Science

Volume

72

Issue

1

First Page

462

Last Page

468

Copyright

© Copyright 1965 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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