When Dr. Thielen first contacted me in connection with this talk, I thought I would discuss some factors that influence the strength of contraction of heart muscle, including human heart muscle. (By including data from humans I felt I could stay within the framework of the general topic of today's seminar.) However, since that time I have been writing a paper on some of my work with isolated strips of heart muscle. This work concerns the relation of the oxygen consumption of the heart to the strength of its contraction, the frequency at which contraction occurs (the heart rate), and the length of the muscle. Out of the reflections over these results has come what is, to my knowledge, an original concept concerning the energy turnover in heart muscle. I would like to show you the path I took in arriving at the tentative conclusion put forth here regarding the relation of the oxygen consumption of the heart and the blood flow through the heart muscle.
Proceedings of the Iowa Academy of Science
©1960 Iowa Academy of Science, Inc.
Whalen, William J.
"Invited Address - The Possible Role of the Coronary Flow in Determining Myocardial Oxygen Consumption,"
Proceedings of the Iowa Academy of Science, 67(1), 66-70.
Available at: https://scholarworks.uni.edu/pias/vol67/iss1/9