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Document Type

Research

Abstract

The antithyroid drug, propylthiouracil (PTU), when fed to white rats at the dietary level of 0.1 percent PTU in finely ground laboratory chow for ten weeks prior to mating, does not affect the ability of either male or female rats to reproduce. All metabolic evidences examined indicate a lower metabolism under the influence of PTU. The PTU dietary treatment was ceased at conception of PTU females. Characteristics of the offspring did not differ from those produced by mothers maintained on normal laboratory chow throughout the experiment.

Publication Date

1960

Journal Title

Proceedings of the Iowa Academy of Science

Volume

67

Issue

1

First Page

463

Last Page

470

Copyright

© Copyright 1960 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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