New-born rats have been irradiated with dosages of 300 to 3,000· roentgens and the effects noted on the skin (histologically) two weeks later. It was found that animals irradiated at temperatures of 0-10 degrees C. were much more resistant to the radiation than those at room temperature. It was also found that at 30 and 35 degrees C. the injury produced was greater than that at 25 degrees C. The effect of the temperature changes appears to be due (at least in part) to alterations produced in metabolic conditions. This conclusion is based on experiments in which the resistance was increased by preventing breathing during the irradiation. It was also found that legs and tails were more resistant if a ligature was applied during the roentgen treatment.
Proceedings of the Iowa Academy of Science
©1941 Iowa Academy of Science, Inc.
Goodrich, J. P.; Evans, T. C.; and Slaughter, J. C.
"Experimental Modification of X-Ray Injury to the Skin of New-Born Rats (Abstract),"
Proceedings of the Iowa Academy of Science, 48(1), 482-482.
Available at: https://scholarworks.uni.edu/pias/vol48/iss1/123