In an earlier paper1 it was reported that when the bromine and chlorine substitution products of vanillin were condensed with acetophenone in the presence of sodium hydroxide, as indicated by Schmidt2 and extended by Claisen and collaborators3, both monoand cliacetophenone derivatives were obtained, regardless of the relative amounts of aldehyde and ketone used. It was clearly of interest to test this behavior when a substituent is present in the acetophenone used. These experiments have been repeated with various substituted acetophenones, and it may be stated at once that although several modifications of the method of condensation were tried4 no diacetophenone derivatives were obtained.
Proceedings of the Iowa Academy of Science
©1938 Iowa Academy of Science, Inc.
Raiford, L. Chas. and Gundy, Glen V.
"α, ß - Unsaturated Ketones Obtained From Acetophenone and Their Reaction with Phenylyhydrazine,"
Proceedings of the Iowa Academy of Science, 45(1), 111-113.
Available at: https://scholarworks.uni.edu/pias/vol45/iss1/21