It has been found that the bromine and chlorine substitution products of vanillin condense with acetophenone in the presence of sodium hydroxide to give mono- and diacetophenone derivatives. Of the vanillalacetophenones, the three monobromo-, the 2,6- and the 5,6-dibromo compounds are yellow; while the 2,5-dibromo and the 2,5,6-tribromo products are practically colorless. The chlorine compounds studied show similar differences. None of the diacetophenone compounds are colored. These products were prepared in order to obtain starting material with which to study further the rearrangement of hydrazones to pyrazolines.
Proceedings of the Iowa Academy of Science
©1932 Iowa Academy of Science, Inc.
Gundy, Glen V. and Raiford, L. Chas.
"Condensation of Vanillin Substitution Products with Acetophenone,"
Proceedings of the Iowa Academy of Science, 39(1), 175-175.
Available at: https://scholarworks.uni.edu/pias/vol39/iss1/37