There is an uncommon demand, particularly in cancer and related studies, for organomagnesium compounds which contain amino groups to increase the solubility of products and also endow them with certain desirable physiological properties. With this in mind a series of Grignard reagents is being prepared, the members of which contain the -MgX group attached to carbon in a molecule having a basic group like -NR2 or in a substituted pyridine, quinoline, etc., grouping. Such RMgX compounds are formed from the corresponding RX compounds with somewhat less ease than from RX compounds having no basic grouping; however, they appear to have the same general properties of RMgX compounds not containing the amino or substituted amino groups.
Proceedings of the Iowa Academy of Science
©1931 Iowa Academy of Science, Inc.
Gilman, Henry; Harris, Stanton A.; and Liu, Chuan
"Organomagnesium Compounds Containing Solubilizing Amino Groups,"
Proceedings of the Iowa Academy of Science, 38(1), 167-168.
Available at: https://scholarworks.uni.edu/pias/vol38/iss1/28