48. Effect of substituents
In a previous report on this study it was found by Raiford and Colbert [Jour. Am. Chem. Soc., 48, 2652 (1926)] that the presence of a nitro radical in diphenyl ether interferes with the entrance of bromine to a much greater degree than could have been predicted on the ground of steric hindrance. Owing to lack of time the structures of several derivatives prepared to test this view were left undetermined for future study. In the present study these have been determined in several cases and a number of other new halogenated derivatives prepared. These experiments have been conducted in the presence of aqueous alkali, a method which was in part standardized and designated in the previous work as the "wet method." In the present work this process has been shown to be capable of two modifications, each with somewhat specific applications which can, in general, be predicted.
Proceedings of the Iowa Academy of Science
©1927 Iowa Academy of Science, Inc.
Raiford, L. Chas. and Thiessen, Garrett
"Effect of Substituents in the Formation and Reactions of Certain Ethers,"
Proceedings of the Iowa Academy of Science, 34(1), 220-221.
Available at: https://scholarworks.uni.edu/pias/vol34/iss1/49