Beadle and Tatum (1945) irradiated bread mold fungus, Neurospora spores, with X-ray and isolated biochemical mutants by their inability to grow in minimal medium. They identified the defective pathways by finding a particular amino acid, vitamin, or nucleotide which, being added to the medium, remedied the defect.
Iowa Science Teachers' Journal
© Copyright 1970 by the Iowa Academy of Science
Dhar, Sujit K.
"Identifying and Growing Biochemical Mutants of Arabidopsis thaliana,"
Iowa Science Teachers Journal: Vol. 7
, Article 8.
Available at: https://scholarworks.uni.edu/istj/vol7/iss3/8