Faculty Publications

Title

Animal models of declining memory in the aged: Short-term and spatial memory in the aged rat

Document Type

Article

Journal/Book/Conference Title

Journals of Gerontology

Volume

35

Issue

3

First Page

355

Last Page

363

Abstract

Short-term and spatial memory were studied in Fischer 344 rats ranging in age from 6 to 26 months of age. Spatial memory, as measured by performance in an 8-armed radial maze, declined gradually with age. In contrast, short-term memory, as measured by retention of previous choices in the spatial maze over short intervals and performance on a modified form of Konorski's discriminated delayed response task, did not decline differentially as a function of age. These findings may be comparable to those obtained in the aged human, who show marked deficits in spatial memory and little change in primary memory under appropriate test conditions.

Original Publication Date

1-1-1980

DOI of published version

10.1093/geronj/35.3.355

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