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Document Type

Research

Keywords

cell death, x-irradiation, histological study, embryonic chicken mandible

Abstract

The sensitive period for the induction by x-irradiation of reduced mandibles in chick embryos was determined to be during the 5th day of incubation. Variations in mandibular anomalies can be correlated with the incidence and frequency of cell deaths. As exhibited by control mandibles, cell deaths around the distal ends of Meckel' s cartilages through the 7th day may aid distal cartilage elongation. The variety of anomalies resulting from teratogenic doses is due, in part, to differences in sensitivity between embryos and their ability to recover from radiation damage. Bone development (initial ossification) in experimental embryos was retarded from 12 to 24 hours. The mandibular bones of the experimental embryos conformed to the abnormally curved and/or bent cartilage; membrane bones were shortened and blunted in their long dimensions.

Publication Date

December 1979

Journal Title

Proceedings of the Iowa Academy of Science

Volume

86

Issue

4

First Page

121

Last Page

128

Copyright

© Copyright 1979 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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