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Document Type

Research

Keywords

Salicyclic acid, chick limb bud, ectodermmesodern interaction, limb bud growth

Abstract

Transplanted hind limb-buds of chick embryos were treated with salicylic acid. Treatment with this chemical caused reduction in length, weight and volume of the developing limb-buds. A side effect observed was an apparent loosening of the basal membrane and examined with regard to length, weight, and volume. The above observations are discussed in relation to the different hypotheses of the ectoderm-mesoderm interaction. The physiological role of the basal membrane, as well as the possible implications of the basal findings to the question of limb development and morphogenesis, are also discussed.

Publication Date

October 1971

Journal Title

Proceedings of the Iowa Academy of Science

Volume

78

Issue

1-2

First Page

20

Last Page

23

Copyright

© Copyright 1971 by the Iowa Academy of Science, Inc.

Language

EN

File Format

application/pdf

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