2-Furanthiocarboxyhydrazones, antibacterial studies
Seven 2-furanthiocarboxyhydrazones were prepared, 5-nitro-furaldehyde-2-furanthiocarboxyhydrazone from the reaction of 2-furanthiocarboxyhydrazide with 5-nitro-2-furaldiacetate and the others from the condensation of 2-furanthiocarboxyhydrazide with aldehydes: 2- furaldehyde, benzaldehyde, p-hydroxybenzaldehyde, o-methoxybenzaldehyde, o-vanillin, and salicylaldehyde. The seven 2-furanthiocarboxyhydrazones were tested for their antibacterial activities against Staphyloccocus aureus and Bacillus subtilis. 5-Nitro-2-furaldehyde-2- furanthiocarboxyhydrazone was found to display the strongest bacterotoxicity.
Journal of the Iowa Academy of Science
© Copyright 1989 by the Iowa Academy of Science, Inc.
Li, Xiaorong; Sun, Zoumin; and Chang, James C.
"Synthesis and Antibacterial Studies of Some 2-Furanthiocarboxyhydrazones,"
The Journal of the Iowa Academy of Science: JIAS: Vol. 96:
, Article 9.
Available at: http://scholarworks.uni.edu/jias/vol96/iss2/9